To begin using your Trezor device, go to trezor.io/start. This site guides you through the setup process. Connect your device to your computer and follow the on-screen instructions to initialize it. You'll create a secure PIN and backup your recovery seed, which is crucial for restoring your wallet if needed. Once set up, you can access your Trezor through the Trezor Suite, where you can manage your cryptocurrencies, check balances, and make transactions securely. Always ensure you're using the official site to avoid phishing scams. Stay safe and protect your digital assets!